Pentobarbital will decrease the level or effect of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of zonisamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of levonorgestrel oral/ethinylestradiol/ferrous bisgl... https://directmysocial.com/story5020517/note-dettagliate-su-pentobarbital-natrium