Assessment revealed that conolidine and cannabidiol substantially blocked Cav2.2 channels. From the peripheral and central anxious process, Cav2.2 channels can be found predominantly at presynaptic terminals32 and play crucial roles in suffering perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds that have an impact on presynaptic Cav2.2 channel https://daveyt739ndt4.wikicommunications.com/user