And finally, clonidine boosts neuraxial opioids and, together with fentanyl, interacts in an additive way, which might lessen the dose of every ingredient by sixty% for postoperative analgesia. Jun 10, 2024 · If clonidine therapy should be to be replaced by a β-blocker, hold off administration of your β-blocker https://www.proleviate.com/post/the-new-pain-killer-conolidine